(Linux, like the well-known Windows, is one of the commonly used operating systems for computers. At present, most bioinformatics software runs on the Linux operating system, so it is essential to learn the Linux operating system before learning bioinformatics. This course is aimed at beginners. Combined with actual cases in bioinformatics analysis work, it will explain the use of Linux operating system and shell programming from simple to deep. The course content involves the popular docker container technology in the IT field, and practically explains the application of container technology in bioinformatics analysis; the course also involves the use of high-performance computing platforms. Students can actually operate the high-performance computing platform and experience the process of big data analysis.)